Sulfadimethoxine+ Ormetoprim premix contains 30% active ingredients (250 g/kg SDM and 50 g/kg OMP)
The potentiated sulfa drug Ormethoxine premix interferes with folic acid production, an essential substance for cell wall synthesis of the bacteria. This takes place on two vital steps. Sulfadimethoxine (SDM) prevents the formation of dihydrofolic acid from para-aminobenzoic acid (PABA) and pteridine. Ormetoprim (OMP) interferes in the following step of transferring dihydrofolic acid into tetrahydrofolic acid, both important steps in the synthesis of bacterial cell walls. As a result, bacteria unable to successfully form cell walls will die allowing the host aquatic animal to overcome the disease.
Ormethoxine premix are recognized as very effective against a wide variety of gram positive and gram negative bacteria like Vibrio, Aeromonas, Edwardsiella and Staphylococcus strains in salmon and trout.
Control of enteric septicemia caused by Edwardsiella ictaluri and furunculosis caused by Aeromonas salmonicida in salmon and trout.
Establish the weight of the fish to be treated. Calculate the amount of feed needed to feed the fish per day according to fish size and water temperature (or recent actual feeding rates). 16.7 grams of Ormethoxine premix is needed per 100 kg of fish weight per day (= 50 mg active ingredient per kg body weight eating 1kg feed per day), as described in Table1. For addition of Ormethoxine premix to feed after pelletization or extrusion, prepare a slurry by suspending Ormethoxine premix in a 5% gelatin solution. Do not use oils as oils tend to bring out the bitter taste of ormetoprim. Gently coat the pelleted feed with the slurry and allow drying for several hours before storage. As a general rule, 1 liter of slurry is required to coat 25 kg of pellets. Refer to dosage levels in Table 2 for recommended level of use
|Daily feed intake(per cent of body weight)||Ormethoxine per metric ton feed (kg)||Biomass fish, shrimp medicated per ton of feed 5 days treatment (kg)|
|Daily feed intake(per cent of body weight)||Ormethoxine premix per liter slurry(gram)||Biomass (fish,shrimp medicated per ton of feed 5 days treatment (kg)|
|Daily feed intake(per cent of body weight)||Ormethoxine per metric ton feed(kg)||Biomass (fish,shrimp)medicated per ton of feed 5 days treatment|
42 days(in water above 10 degree Celsius)
When handling the product, use proper personal protective equipment
like gloves, anti dust mask and safety glasses as it leads to sever eye reaction.
In case of accidental eye exposure ,wash the place with plenty of water.
Avoid skin contact strictly.
Keep out of reach of children.
Store out of direct sunlight in a well ventilated area at room
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