Dectomectin®


Doramectin1%

دکتومکتین® | ‌®Dectomectin
  • - animals:
  • - Packaging:
  • 50 ml vial

Product properties

Composition

Each ml contains 10 mg doramectin

Mechanism of Action:

Doramectin, a long lasting and broad spectrum endectocide, is a member of the macrocyclic lactone class. Doramectin acts as an agonist of the GABA (gamma-amino butyric acid) neurotransmitter in nerve cells and also binds to glutamate-gated chloride channels in nerve and muscle cells of invertebrates. In both cases it blocks the transmission of neuronal signals of the parasites and leads to death of parasites.

Since flukes and tapeworms do not use GABA as a neurotransmitter doramectin is ineffective against these parasites.

Indications of use

Doramectin is effective against many internal and external parasites.

Doramectin treats and controls gastrointestinal round worms, lung worms, suckling lice, mange mites, screw worms, single host ticks, nasal worm, sheep scab and itch mites and aids in control of blow fly.

Dosage and route of administration

only with veterinarian prescription.

Cattle, camel and buffalo: Inject either into the muscle or under the skin of neck,1 ml per 50 kg body weight (equivalent to 0.2 mg per kg body weight).

Sheep and goat: Inject either into the muscle or under the skin of neck,1-1.5 ml per 50 kg body weight (equivalent to 0.2-0.3mg per kg body weight).

Withdrawal Time

35 days

Do not use in animals producing milk for human consumption.

Contraindication:

Doramectin should not be used in animals that produce milk intended for human consumption.

Precautions

The dosage of drug should not be exceeded from the recommended dose.

Overdose of product leads to neurologic symptoms such as depression and ataxia.

The sterile condition during the injection should be considered.

Keep out of reach of children.

Environmental safety:

When doramectin comes in contact with the soil, it readily and tightly binds to the soil and becomes inactive over time. Free doramectin may adversely affect fish and certain water-borne organisms on which they feed. For this reason  dispose the empty containers in an approved landfill or by incineration.

Storage conditions

Store below 25º C and protect from sunlight.

After the first opening of the vial the shelf life is 28 days.